Prevention of cardiovascular disease: Omega-3s would be ineffective

Prevention of cardiovascular disease: Omega-3s would be ineffective. In people with diabetes, the consumption of omega-3 would not be effective in limiting the risk of cardiovascular diseases such as heart attacks or strokes.

Prevention of cardiovascular disease: Omega-3s would be ineffective

They are naturally present in oily fish, rapeseed oil, linseed or nuts and would be beneficial for the heart. But do omega-3s deserve the good health status they enjoy? A group of researchers from the University of Oxford (United Kingdom) * publishes, on August 26, 2018, a study on the effect of omega-3 supplementation on the health of diabetics in the New England Journal of Medicine . According to these scientists, omega-3s would not have a positive effect on the cardiovascular health of people with diabetes.

As many cardiovascular events as with no omega-3

British researchers supported their research on a total of 15,480 diabetic patients over 40 years of age and initially without cardiovascular disease. Half of them (7,740 people) received one capsule of one gram of omega-3 to be taken each day and the other half (7,740 people too) received a daily placebo capsule that contained olive oil, rich in omega-9. All of these participants then had to answer a questionnaire sent every six months for an average of seven years. In parallel, 1,800 randomly selected participants underwent blood and urine tests, weighing and blood pressure measurements.

Results:

• So many people have followed the trial in both groups, omega-3 and placebo;
• Similar rates of severe cardiovascular events ( nonfatal myocardial infarction, stroke, or transient ischemic attack ) were observed in both groups (689 patients in the omega-3 group and 712 in the placebo group);
• The mortality rates observed in the two groups were also comparable (752 deaths in the omega-3 group and 788 in the placebo group).

Two to three times more cardiovascular disease in diabetics

The researchers behind this study conclude that in terms of cardiovascular protection, there is no significant difference between people who take omega-3s and those who do not. According to these scientists, encouraging people with diabetes to consume more omega-3 to limit cardiovascular risks would therefore be an ineffective measure.

The diabetes can lead to cardiovascular complications  "because it also affects the large blood vessels (arteries of the neck, legs, heart...)" recalls the French Federation of Diabetics on its website. "The complications of the heart and arteries are two to three times more common in diabetics than in the rest of the population." This is why British researchers have chosen to focus their work on these people, who must receive regular cardiovascular monitoring.

* Study sponsored by Oxford University in collaboration with the British Heart Foundation, Bayer, EPD Research Ltd. and the Medical Research Council enrolled in the clinical trial ASCEND for A Study of Cardiovascular Events iN Diabetes.

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